Nandhakumar,
If you're analyzing a mechanism, you would probably be using the Mechanism Dynamics Option (MDO) in Creo Parametric. Back in the day that used to be part of Mechanica (the precursor to Creo Simulate) but now it's its own separate module. With MDO, you can perform Dynamics analysis that incorporates mass / inertia, springs, forces, moments, and so on.
You can take the resulting forces and use them as load cases in Creo Simulate, for example, in a static or dynamic time-varying analysis.
Creo Simulate can be used to perform analysis on both parts and assemblies.
Dave